TheHubCity on a HillAthens of AmericaBeantownCity of ChampionChemical Biology Conference
Cambridge, USA, September 14th 2023
Photos from the 2019 Symposium
The 2019 Committee and Speakers
Thank you all for your participation in the 2019 Chemical Biology in the Hub symposium!
Chris Am Ende
Small tools to answer big questions - advancing chemical biology through innovative chemistry
Niyi Fadeyi
Mapping of immunomodulatory receptor protein interactions via photoactivation-based proximity labeling of the cell surface - Part 1
Rob Oslund
Mapping of immunomodulatory receptor protein interactions via photoactivation-based proximity labeling of the cell surface - Part 2
Pat Walters
Applications of Artificial Intelligence in Drug Discovery - Separating Hype From Utility
NESACS Sponsored event
The Chemical Biology in the Hub conference would not be possible without the support of the New England chapter of the American Chemical Society (NESACS)
The organizing comity would like to thank NESACS for its ongoing support
Visit NESACSAbout the Conference
The science will focus cutting edge research in Chemical Biology from both academic and industry labs in the areas of machine learning applied to drug discovery, translational chemical biology, targeted protein degradation, chemical proteomics, novel target identification/validation, forward thinking synthetic strategies for chemical biology and chemical imaging.
The symposium will be followed by a reception with appetizers and refreshments for the symposium speakers and attendees. We anticipate that there will be approximately 240 attendees. Our target audience is a diverse mix of chemical biologists, including students and professionals from industry and academia.
The symposium will be followed by a reception with appetizers and refreshments for the symposium speakers and attendees. We anticipate that there will be approximately 240 attendees. Our target audience is a diverse mix of chemical biologists, including students and professionals from industry and academia.
1
Machine Learning
2
Translational Chemical Biology
3
Targeted Protein Degradation
4
Target Identification
5
Chemical Imaging
Conference Schedule - September 14th 2023
8:15 – 9:00 am | Registration and coffee |
9:00 – 9:10 am | Opening remarks |
9:10 – 9:45 amEd Chouchani, Harvard University | Systematic discovery of druggable redox switches on immunological proteins |
9:45 – 10:20 amDanette Daniels, Foghorn Therapeutics | Targeting Chromatin Regulatory Proteins with Therapeutic Degraders |
10:20 – 10:45 am | Coffee Break |
10:45 – 11:20 amKeriann Backus, UCLA | Global rewiring of the proteome by cysteine-reactive electrophiles |
11:20 – 11:55 amBen Ruprecht, Covant Therapeutics | Leaving a permanent mark – Harnessing covalent chemoproteomics to target native proteoforms |
11:55 am – 1:00 pm | Lunch |
1:00 – 1:35 pmJustin Kim, DFCI | Bioorthogonally activated reactive species for target identification |
1:35 – 2:10 pmHeather Murrey, Scorpion Therapeutics | Advances in Covalent Ligand Discovery Enable Development of New Cancer Therapeutics |
2:10 – 2:45 pmJustin Rettenmaier & Matt Labenski, Jnana Therapeutics | RAPID: photoaffinity-based high-throughput ligand discovery in cells |
2:45 – 3:05 pm | Coffee break |
3:05 – 3:40 pmJonathan Hurov, FogPharma | Development of Stapled Peptide Helicons™ for Inhibition of ß-Catenin:TCF Interaction |
3:40 – 4:15 pmMichelle Arkin, UCSF | Structure, function, and manipulation of ‘hub’ proteins and their partners |
4:15 – 4:20 pm | Closing remarks |
4:20 – 6:30 pm | Poster session and reception |
8:15 – 9:00 am | Registration and coffee |
9:00 – 9:10 am | Opening remarks |
9:10 – 9:45 amEd Chouchani, Harvard University | Systematic discovery of druggable redox switches on immunological proteins |
9:45 – 10:20 amDanette Daniels, Foghorn Therapeutics | Targeting Chromatin Regulatory Proteins with Therapeutic Degraders |
10:20 – 10:45 am | Coffee Break |
10:45 – 11:20 amKeriann Backus, UCLA | Global rewiring of the proteome by cysteine-reactive electrophiles |
11:20 – 11:55 amBen Ruprecht, Covant Therapeutics | Leaving a permanent mark – Harnessing covalent chemoproteomics to target native proteoforms |
11:55 am – 1:00 pm | Lunch |
1:00 – 1:35 pmJustin Kim, DFCI | Bioorthogonally activated reactive species for target identification |
1:35 – 2:10 pmHeather Murrey, Scorpion Therapeutics | Advances in Covalent Ligand Discovery Enable Development of New Cancer Therapeutics |
2:10 – 2:45 pmJustin Rettenmaier & Matt Labenski, Jnana Therapeutics | RAPID: photoaffinity-based high-throughput ligand discovery in cells |
2:45 – 3:05 pm | Coffee break |
3:05 – 3:40 pmJonathan Hurov, FogPharma | Development of Stapled Peptide Helicons™ for Inhibition of ß-Catenin:TCF Interaction |
3:40 – 4:15 pmMichelle Arkin, UCSF | Structure, function, and manipulation of ‘hub’ proteins and their partners |
4:15 – 4:20 pm | Closing remarks |
4:20 – 6:30 pm | Poster session and reception |
BUY CONFERENCE TICKETS (August 17th 2023)
Conference tickets will be on sale August 17h 2023 at 12:00pm from the NESACS Eventbrite page. Don't miss the release, set up a reminder from the Eventbrite page.
Our 2023 Speakers
Michelle ArkinUCSF
San Francisco, CA
Jonathan HurovFogPharma
Cambridge, MA
Justin RettenmaierJnana Therapeutics
Boston, MA
Keriann BackusUCLA
Los Angeles, CA
Justin KimDFCI
Boston, MA USA
Ben RuprechtCovant Therapeutics
Boston, MA
Ed ChouchaniHarvard University
Cambridge, MA
Matt LabenskiJnana Therapeutics
Boston, MA
Danette DanielsFoghorn Therapeutics
Cambridge, MA
Heather MurreyScorpion Therapeutics
Boston, MA
Conference Location
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